Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28638632 | 0.80 | LMNA (0.41) | BCHE | |
| SCHEMBL27788767 | 0.71 | LMNA (0.43) | BCHE | |
| SCHEMBL28031307 | 0.70 | TSHR (0.40) | OPRM1OPRL1 | |
| SCHEMBL19598518 | 0.68 | OPRM1 (0.41) | BCHEMAPTCYP2C19OPRM1OPRL1 | |
| SCHEMBL28201268 | 0.68 | TSHR (0.39) | OPRM1OPRL1 | |
| SCHEMBL15674250 | 0.67 | OPRM1 (0.40) | OPRM1OPRL1GRM2GRM3PDPK1 | |
| SCHEMBL24792758 | 0.67 | OPRM1 (0.47) | OPRM1OPRL1PDPK1MTOR | |
| SCHEMBL24792755 | 0.67 | OPRM1 (0.47) | OPRM1OPRL1PDPK1MTOR | |
| SCHEMBL24792759 | 0.67 | OPRM1 (0.47) | OPRM1OPRL1PDPK1MTOR | |
| SCHEMBL30137974 | 0.67 | OPRM1 (0.47) | OPRM1OPRL1PDPK1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2938190-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2015-11-04 | — | — | EP | disclosed |
| WO-2014105817-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2014-07-03 | — | — | WO | disclosed |