Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28031307 | 0.91 | TSHR (0.40) | TSHROPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL21753776 | 0.80 | LMNA (0.42) | TSHRLMNA | |
| SCHEMBL28200687 | 0.79 | NR5A2 (0.36) | TSHRNR5A2OPRM1OPRD1OPRK1 | |
| SCHEMBL28102974 | 0.76 | LMNA (0.44) | TSHRLMNA | |
| SCHEMBL29015942 | 0.73 | SMYD2 (0.36) | NR5A2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL8601625 | 0.70 | OPRM1 (0.39) | TSHRNR5A2OPRM1OPRD1OPRK1 | |
| SCHEMBL2502222 | 0.70 | NR5A2 (0.37) | TSHRNR5A2OPRM1OPRD1OPRK1 | |
| SCHEMBL21504377 | 0.69 | SCN1A (0.40) | TSHRNR5A2OPRM1OPRL1SCN1A | |
| SCHEMBL15465575 | 0.69 | CTSV (0.36) | NR5A2OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL15465574 | 0.69 | CTSV (0.36) | NR5A2OPRM1OPRD1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709332-A | A kind of C, O loop coil aryl glycoside class compound and its preparation and application | 中国科学院上海药物研究所 | 2018-02-16 | — | — | CN | disclosed |