Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | EPAS1 | Q99814 | 7/20 | 0.34 |
| ▸ | VEGFA | P15692 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.31 |
| ▸ | ACLY | P53396 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28822186 | 0.80 | ALPL (0.35) | TRPV4CA1CA2CA9STS | |
| SCHEMBL5551444 | 0.76 | CA1 (0.35) | CA1CA2CA9 | |
| SCHEMBL2192941 | 0.76 | TRPA1 (0.34) | TRPV4 | |
| SCHEMBL8618260 | 0.73 | EPAS1 (0.53) | PDE4APDE4CPDE4DTRPV4AKR1C3 | |
| SCHEMBL1195899 | 0.72 | HSD11B1 (0.45) | PDE4APDE4CPDE4DTRPV4AKR1C3 | |
| SCHEMBL5108353 | 0.72 | CA1 (0.61) | PDE4APDE4CPDE4DTRPV4CA1 | |
| SCHEMBL5728291 | 0.71 | EPAS1 (0.45) | PDE4APDE4CPDE4DTRPV4AKR1C3 | |
| SCHEMBL21723413 | 0.71 | SLC22A12 (0.41) | PDE4APDE4CPDE4DTRPV4AKR1C3 | |
| SCHEMBL31245789 | 0.71 | SLC22A12 (0.41) | PDE4APDE4CPDE4DTRPV4AKR1C3 | |
| SCHEMBL23829 | 0.70 | CXCR2 (0.34) | CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105008378-A | Reaction catalyst for cross coupling and method for manufacturing aromatic compound | HOKKO CHEM IND CO | 2015-10-28 | — | — | CN | disclosed |