Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PAK4 | O96013 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | LTK | P29376 | 1/20 | 0.35 |
| ▸ | GRK5 | P34947 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537049 | 0.86 | ALDH1A1 (0.30) | — | |
| SCHEMBL6650232 | 0.83 | PTGS2 (0.36) | PTGS2 | |
| SCHEMBL26190 | 0.82 | ALDH1A1 (0.37) | PTGS2MAP4K4CSF1RFGFR1LTK | |
| SCHEMBL28030817 | 0.81 | ALDH1A1 (0.35) | LCKCSF1RFGFR1PRKACAKDR | |
| SCHEMBL28031409 | 0.81 | PTGS2 (0.40) | PTGS2PTGS1SLC6A4SLC6A3HTR7 | |
| SCHEMBL27463443 | 0.81 | ALDH1A1 (0.35) | PTGS2MAP4K4CSF1RFGFR1LTK | |
| SCHEMBL28030819 | 0.79 | HRH3 (0.43) | — | |
| SCHEMBL6012037 | 0.77 | TSHR (0.36) | PTAFR | |
| SCHEMBL18696022 | 0.77 | PTAFR (0.36) | PTAFR | |
| SCHEMBL28150039 | 0.77 | ABL1 (0.46) | PTGS2PTGS1ABL1CLK4HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105008408-B | METHOD FOR PRODUCING ETHYLENE/[alpha]-OLEFIN COPOLYMER | 日本聚乙烯株式会社 | 2017-05-10 | — | — | CN | disclosed |
| CN-105026408-A | Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer | JAPAN POLYETHYLENE CORP | 2015-11-04 | — | — | CN | disclosed |
| CN-105008408-A | METHOD FOR PRODUCING ETHYLENE/[alpha]-OLEFIN COPOLYMER | JAPAN POLYETHYLENE CORP | 2015-10-28 | — | — | CN | disclosed |