SCHEMBL28031409

SCHEMBL28031409

Clc1ccc(-c2cccc3c2C=C[CH]3)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.40
PTGS1 P23219 1/20 0.36
CYP1A2 P05177 1/20 0.35
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
AHR P35869 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
CRHR1 P34998 1/20 0.31
HTR1A P08908 2/20 0.31
HTR7 P34969 2/20 0.31
PTAFR P25105 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
CASP3 P42574 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6537049 0.86 ALDH1A1 (0.30) ALDH1A1HSD17B10
SCHEMBL6650232 0.83 PTGS2 (0.36) PTGS2CYP1A2MEN1KMT2ANPC1
SCHEMBL26190 0.82 ALDH1A1 (0.37) PTGS2ALDH1A1HSD17B10
SCHEMBL28030817 0.81 ALDH1A1 (0.35) CYP1A2SLC6A3MEN1KMT2ANPC1
SCHEMBL28031393 0.81 PTGS2 (0.40) PTGS2PTGS1SLC6A4SLC6A3HTR1A
SCHEMBL27463443 0.81 ALDH1A1 (0.35) PTGS2ALDH1A1HSD17B10
SCHEMBL28031388 0.81 MAPT (0.36) MEN1KMT2ANPC1RAB9ATP53
SCHEMBL20972417 0.80 CYP2A6 (0.36) PTGS2ALDH1A1HSD17B10
SCHEMBL27462619 0.80 CYP2A6 (0.36) PTGS2ALDH1A1HSD17B10
SCHEMBL27463823 0.80 CYP2A6 (0.36) PTGS2ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106279485-B Polyvinyls, catalyst for olefines polymerizing ingredient, the catalyst for olefines polymerizing comprising the ingredient and the method using catalyst production polyvinyls 日本聚乙烯株式会社 2018-10-02 CN disclosed
CN-106279485-A Polyvinyls, polythylene resin composition and application thereof, catalyst for olefines polymerizing composition, the catalyst for olefines polymerizing comprising described composition and the method using described Catalyst Production polyvinyls 日本聚乙烯株式会社 2017-01-04 CN disclosed
CN-103582669-B Ethylene polymer, polyethylene resin composition and use thereof, catalyst component for olefin polymerization, catalyst for olefin polymerization comprising the component, and method for producing ethylene polymer using the catalyst 日本聚乙烯株式会社 2016-08-31 CN disclosed
CN-105026408-A Metallocene compound, catalyst for olefin polymer, method for producing olefin polymer, and olefin polymer JAPAN POLYETHYLENE CORP 2015-11-04 CN disclosed
CN-105008408-A METHOD FOR PRODUCING ETHYLENE/[alpha]-OLEFIN COPOLYMER JAPAN POLYETHYLENE CORP 2015-10-28 CN disclosed
CN-103582669-A Ethylene polymer, polyethylene resin composition and use thereof, catalyst component for olefin polymerization, catalyst for olefin polymerization comprising the component, and method for producing ethylene polymer using the catalyst JAPAN POLYETHYLENE CORP 2014-02-12 CN disclosed