Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | KLK1 | P06870 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | THRA | P10827 | 6/20 | 0.38 |
| ▸ | THRB | P10828 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12370664 | 0.78 | KLK1 (0.44) | HRH3KLK1KDM4ETHRATHRB | |
| SCHEMBL7636855 | 0.75 | KMT2A (0.49) | HRH3KLK1KDM4ETHRATHRB | |
| SCHEMBL2349299 | 0.74 | KLK1 (0.39) | HRH3KLK1KDM4ETHRATHRB | |
| SCHEMBL20815429 | 0.74 | ALDH1A1 (0.58) | THRATHRBALDH1A1 | |
| SCHEMBL8788764 | 0.73 | THRB (0.44) | HRH3KLK1THRATHRBMEN1 | |
| SCHEMBL27320400 | 0.73 | THRB (0.48) | HRH3KLK1KDM4ETHRATHRB | |
| SCHEMBL1545057 | 0.71 | KLK1 (0.47) | HRH3KLK1KDM4ETHRATHRB | |
| SCHEMBL12370674 | 0.70 | ALDH1A1 (0.58) | HRH3KLK1KDM4ETHRATHRB | |
| SCHEMBL20482100 | 0.70 | SMN1; SMN2 (0.39) | HRH3KLK1KDM4ETHRATHRB | |
| SCHEMBL8350687 | 0.68 | KLK1 (0.35) | HRH3KLK1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102300921-B | Based on the binder composition of grafted polyethylene | ARKEMA FRANCE (FR) | 2015-09-02 | — | — | CN | disclosed |