SCHEMBL28031663

SCHEMBL28031663

NC(=O)C(c1c(Cl)cc(Cl)cc1Cl)c1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
TSHR P16473 3/20 0.40
HSD17B10 Q99714 2/20 0.40
CYP3A4 P08684 1/20 0.40
RECQL P46063 1/20 0.40
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 1/20 0.39
AKR1C4 P17516 1/20 0.39
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
AKR1C1 Q04828 1/20 0.39
KDM4E B2RXH2 2/20 0.37
GLA P06280 1/20 0.37
GAA P10253 1/20 0.37
EPHX1 P07099 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
TPMT P51580 1/20 0.36
HPGD P15428 1/20 0.36
CASP1 P29466 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10754738 0.77 KDM4E (0.37) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL1002836 0.70 ALDH1A1 (0.43) ALDH1A1TSHRHSD17B10CYP3A4RECQL
1,3,5-Trichlorobenzene SCHEMBL29192936 0.70 TSHR (0.57) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL31603827 0.69 MEN1 (0.44) EPHX1L3MBTL1MEN1KMT2A
SCHEMBL28510114 0.68 TPMT (0.42) ALDH1A1TSHRCYP3A4GAAEPHX1
SCHEMBL8525339 0.68 AKR1C4 (0.45) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL14335016 0.68 POLB (0.37) ALDH1A1TSHRGAAL3MBTL1TPMT
SCHEMBL17351119 0.67 SPR (0.40) ALDH1A1TSHRHSD17B10CYP3A4RECQL
SCHEMBL10788837 0.67 ALDH1A1 (0.40) ALDH1A1TSHRHSD17B10CYP3A4RECQL
Urea SCHEMBL29192961 0.67 AKR1C4 (0.48) ALDH1A1TSHRHSD17B10CYP3A4RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105017067-B Synthetic method of one kind 2 chlorine N (2,4 dichlorophenyl) imines for chloroacetic chloride 江苏威格瑞斯化工有限公司 2017-12-15 CN disclosed
CN-105017067-A Synthetic method of 2-chlorine-N-(2,4-dichlorophenyl)-imide acetylchloride JIANGSU VICITORIES CHEMICALS CO LTD 2015-11-04 CN disclosed