Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28031664 | 0.90 | KDM4E (0.40) | PDE10AKDM4ETSHRHPGDALDH1A1 | |
| SCHEMBL28822266 | 0.82 | GPR3 (0.47) | PDE10AKDM4ECYP2C19CYP3A4MEN1 | |
| SCHEMBL28031135 | 0.81 | GPR3 (0.42) | KDM4EALDH1A1GAASMN1; SMN2NPC1 | |
| SCHEMBL28031751 | 0.80 | GPR3 (0.38) | KDM4EDHODHSMN1; SMN2CYP2C19CYP2C9 | |
| SCHEMBL28031124 | 0.80 | DHODH (0.39) | PDE10AKDM4EHPGDDHODHSMN1; SMN2 | |
| SCHEMBL28031125 | 0.79 | KDM4E (0.44) | KDM4ETSHRHPGDALDH1A1GAA | |
| SCHEMBL28031746 | 0.77 | MAT2A (0.39) | DHODHLMNAGPR3 | |
| SCHEMBL28031123 | 0.77 | KDM4E (0.36) | KDM4EHPGDALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28031119 | 0.74 | SMN1; SMN2 (0.35) | KDM4ETSHRHPGDALDH1A1GAA | |
| SCHEMBL28031691 | 0.72 | KDM4E (0.41) | KDM4EALDH1A1DHODHNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104844651-A | Method for preparing six fluorine phosphonic acid ester base fe organism derivatives | UNIV LUOYANG NORMAL | 2015-08-19 | — | — | CN | disclosed |