Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21437134 | 0.83 | CYP3A4 (0.39) | CHKAGAAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL28031673 | 0.81 | MAPT (0.42) | GAAMAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL31345554 | 0.80 | MAPT (0.49) | GAAMAPTSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL27771874 | 0.78 | MAPT (0.38) | GAAMAPTSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL28032380 | 0.77 | MEN1 (0.38) | GAAMAPTSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL19501004 | 0.74 | NPC1 (0.45) | CHKAGAAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL12143524 | 0.72 | NPC1 (0.40) | GAAMAPTKDM4EKMT2ANPC1 | |
| SCHEMBL19107746 | 0.72 | MAPT (0.41) | GAAMAPTSMN1; SMN2KDM4EKMT2A | |
| SCHEMBL40317 | 0.72 | NPC1 (0.40) | GAAMAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL25882938 | 0.71 | ITGB3 (0.41) | GAAMAPTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104926749-A | Benzoxazine monomer comprising vinyl benzene structure, and application and preparation method of benzoxazine monomer | UNIV HUAZHONG SCIENCE TECH | 2015-09-23 | — | — | CN | disclosed |