SCHEMBL40317

SCHEMBL40317

c1ccc(N2COc3ccc(Cc4ccc5c(c4)CN(c4ccccc4)CO5)cc3C2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
MAPT P10636 2/20 0.40
VDR P11473 1/20 0.39
KDM4E B2RXH2 1/20 0.38
CYP2D6 P10635 2/20 0.38
CYP3A4 P08684 1/20 0.38
HIF1A Q16665 1/20 0.38
DRD4 P21917 3/20 0.36
DRD2 P14416 2/20 0.36
DRD3 P35462 2/20 0.36
ACLY P53396 1/20 0.35
GAA P10253 2/20 0.33
ADORA1 P30542 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KDM1A O60341 1/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
POLB P06746 1/20 0.33
ADRA2A P08913 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12143524 0.97 NPC1 (0.40) NPC1RAB9AMAPTVDRKDM4E
SCHEMBL22384638 0.92 FAAH (0.35) NPC1RAB9AMAPTVDRKDM4E
SCHEMBL24445535 0.90 EED (0.39) NPC1RAB9AMAPTDRD4DRD2
SCHEMBL16084554 0.89 OXTR (0.42) NPC1RAB9AMAPTVDRKDM4E
SCHEMBL21437134 0.88 CYP3A4 (0.39) NPC1RAB9AMAPTVDRKDM4E
SCHEMBL19751520 0.88 CYP3A4 (0.34) NPC1RAB9AMAPTVDRKDM4E
SCHEMBL12143533 0.86 VDR (0.35) NPC1RAB9AMAPTVDRKDM4E
SCHEMBL12143525 0.86 NPC1 (0.35) NPC1RAB9AMAPTVDRKDM4E
SCHEMBL19107746 0.85 MAPT (0.41) NPC1RAB9AMAPTVDRKDM4E
SCHEMBL24383870 0.85 DRD2 (0.31) NPC1RAB9AMAPTVDRCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 378 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030992-B2 Photocurable composition CANON KABUSHIKI KAISHA (JP) 2024-07-09 US disclosed
US-12018154-B2 Rubber composition offering high stiffness and low hysteresis THE GOODYEAR TIRE & RUBBER COMPANY (US) 2024-06-25 US disclosed
US-12018154-B2 Rubber composition offering high stiffness and low hysteresis THE GOODYEAR TIRE & RUBBER COMPANY (US) 2024-06-25 US disclosed
US-20240189849-A1 Method and System for Switching a Dispensed Fluid in a Nanofabrication Dispensing System CANON KABUSHIKI KAISHA (JP) 2024-06-13 US disclosed
US-11951660-B2 Shaping system including an evaporation cover, shaping process, and method of manufacturing an article CANON KABUSHIKI KAISHA (JP) 2024-04-09 US disclosed
US-20240026069-A1 POLYMER, COMPOSITION, CURED PRODUCT, LAMINATE, AND ELECTRONIC COMPONENT JSR CORPORATION (JP) 2024-01-25 US disclosed
US-20240026069-A1 POLYMER, COMPOSITION, CURED PRODUCT, LAMINATE, AND ELECTRONIC COMPONENT JSR CORPORATION (JP) 2024-01-25 US disclosed
US-20230345631-A1 PREPREG, METAL-CLAD LAMINATE, AND PRINTED WIRING BOARD JSR CORPORATION (JP) 2023-10-26 US disclosed
US-20230345631-A1 PREPREG, METAL-CLAD LAMINATE, AND PRINTED WIRING BOARD JSR CORPORATION (JP) 2023-10-26 US disclosed
US-11780772-B2 Glass-resin composite-based multi-composite material COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2023-10-10 US disclosed
US-20080076886-A1 Backbones of polyethers, perfluorinated polyethers, polydimethylsiloxanes and hydroxy terminated polybutadienes coupled to phenyl, biphenyl, bisphenol A, bisphenol F, bisphenol S, bisphenol E, allyl, alkyl, alkenyl, carboxy, N-carbamoyl, cyclic amides, epoxy and a thermosetting component; toughening LOCTITE (R&D) LIMITED 2008-03-27 US disclosed
US-20080076886-A1 Backbones of polyethers, perfluorinated polyethers, polydimethylsiloxanes and hydroxy terminated polybutadienes coupled to phenyl, biphenyl, bisphenol A, bisphenol F, bisphenol S, bisphenol E, allyl, alkyl, alkenyl, carboxy, N-carbamoyl, cyclic amides, epoxy and a thermosetting component; toughening LOCTITE (R&D) LIMITED 2008-03-27 US disclosed
US-7312534-B2 Interlayer dielectric and pre-applied die attach adhesive materials HENKEL CORPORATION (US) 2007-12-25 US disclosed
US-7312534-B2 Interlayer dielectric and pre-applied die attach adhesive materials HENKEL CORPORATION (US) 2007-12-25 US disclosed
US-20070278683-A1 Interlayer Dielectric and Pre-Applied Die Attach Adhesive Materials HENKEL CORPORATION (US) 2007-12-06 US disclosed
US-20070278683-A1 Interlayer Dielectric and Pre-Applied Die Attach Adhesive Materials HENKEL CORPORATION (US) 2007-12-06 US disclosed
US-20070129509-A1 Curable compositions HENKEL CORPORATION 2007-06-07 US disclosed
US-20070129509-A1 Curable compositions HENKEL CORPORATION 2007-06-07 US disclosed
US-20070007692-A1 Curable compositions for advanced processes, and products made therefrom Henkel IP & Holding GmbH (DE) 2007-01-11 US disclosed
US-20070007692-A1 Curable compositions for advanced processes, and products made therefrom Henkel IP & Holding GmbH (DE) 2007-01-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070129509-A1 Curable compositions CBX4, CBX7, KDM5C NPC1 4543/4885RAB9A 4196/4885MAPT 1565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.