Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 4/20 | 0.57 |
| ▸ | THRA | P10827 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.54 |
| ▸ | METAP1 | P53582 | 7/20 | 0.52 |
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.49 |
| ▸ | CYP27A1 | Q02318 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8014606 | 0.87 | METAP1 (0.59) | CYP26A1THRATHRBMETAP1CYP24A1 | |
| SCHEMBL7592165 | 0.87 | METAP1 (0.59) | CYP26A1THRATHRBMETAP1CYP24A1 | |
| SCHEMBL2125675 | 0.82 | METAP1 (0.71) | THRATHRBMETAP1 | |
| SCHEMBL8003063 | 0.82 | METAP1 (0.71) | THRATHRBMETAP1 | |
| Hydrochloric Acid SCHEMBL2125507 | 0.80 | METAP1 (0.72) | THRATHRBMETAP1 | |
| SCHEMBL11730548 | 0.80 | THRA (0.58) | CYP26A1THRATHRBMETAP1CYP24A1 | |
| SCHEMBL11724446 | 0.80 | METAP1 (0.72) | CYP26A1THRATHRBMETAP1CYP24A1 | |
| SCHEMBL8012038 | 0.78 | METAP1 (0.78) | CYP26A1THRATHRBMETAP1CYP24A1 | |
| SCHEMBL7590283 | 0.78 | METAP1 (0.78) | CYP26A1THRATHRBMETAP1CYP24A1 | |
| Hydrochloric Acid SCHEMBL10341505 | 0.77 | METAP1 (0.78) | CYP26A1THRATHRBMETAP1CYP24A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105017037-A | 6-substituted aryl amino methyl tetrahydronaphthalene derivative or salt thereof and preparation method and application of 6-substituted aryl amino methyl tetrahydronaphthalene derivative | UNIV FUDAN | 2015-11-04 | — | — | CN | disclosed |