Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL548670 | 1.00 | PTPN1 (0.39) | PTPN1PTPN2MEN1KMT2AHSP90AA1 | |
| SCHEMBL548149 | 0.86 | MEN1 (0.42) | PTPN1PTPN2MEN1KMT2AHSP90AA1 | |
| SCHEMBL547866 | 0.82 | CA1 (0.39) | PTPN1PTPN2MEN1KMT2AHSP90AA1 | |
| SCHEMBL548288 | 0.82 | MEN1 (0.39) | MEN1KMT2AHSP90AA1MAPTLMNA | |
| SCHEMBL548380 | 0.79 | DDR2 (0.42) | PTPN1PTPN2MEN1KMT2AHSP90AA1 | |
| SCHEMBL547722 | 0.78 | MEN1 (0.42) | MEN1KMT2AHSP90AA1MAPTLMNA | |
| SCHEMBL548577 | 0.70 | ALDH1A1 (0.36) | MEN1KMT2AHSP90AA1MAPTLMNA | |
| SCHEMBL548148 | 0.69 | KDM4E (0.48) | PTPN1MEN1KMT2AMAPTLMNA | |
| SCHEMBL11563555 | 0.68 | CA1 (0.49) | PTPN1MEN1KMT2AMAPTLMNA | |
| SCHEMBL8784386 | 0.67 | ALDH1A1 (0.43) | MAPTLMNAHTTKDM4ECA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4274565-B1 | SOY ISOFLAVONES FOR USE IN ASTHMA PREVENTION IN A PATIENT HAVING A PLASMINOGEN ACTIVATOR INHIBITOR 1 (PAI-1) RISK GENOTYPE | UNIV SOUTH FLORIDA (US) | 2026-04-22 | — | — | EP | disclosed |
| US-20240415802-A1 | GENISTEIN FOR ASTHMA TREATMENT | Ann & Robert H. Lurie Children's Hospital of Chicago | 2024-12-19 | — | — | US | disclosed |
| US-20240139223-A1 | SOY ISOFLAVONES FOR ASTHMA PREVENTION | Ann & Robert H. Lurie Children's Hospital of Chicago | 2024-05-02 | — | — | US | disclosed |
| EP-4274565-A1 | SOY ISOFLAVONES FOR ASTHMA PREVENTION | University of South Florida (US) | 2023-11-15 | — | — | EP | disclosed |
| WO-2023177676-A1 | GENISTEIN FOR ASTHMA TREATMENT | UNIVERSITY OF SOUTH FLORIDA (US) | 2023-09-21 | — | — | WO | disclosed |
| WO-2022150770-A1 | SOY ISOFLAVONES FOR ASTHMA PREVENTION | UNIVERSITY OF SOUTH FLORIDA (US) | 2022-07-14 | — | — | WO | disclosed |