Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28031629 | 0.93 | KDM4E (0.47) | GFERKDM4EALDH1A1TDP1PTPN11 | |
| SCHEMBL28194102 | 0.90 | MEN1 (0.43) | KDM4EALDH1A1GABRA1GABRG2GABRB3 | |
| SCHEMBL28031631 | 0.90 | PTPN11 (0.47) | GFERKDM4EALDH1A1TDP1PTPN11 | |
| SCHEMBL28031707 | 0.85 | ALDH1A1 (0.46) | GFERKDM4EALDH1A1TDP1PTPN11 | |
| SCHEMBL28031643 | 0.83 | MEN1 (0.44) | KDM4EALDH1A1TDP1GABRA1GABRG2 | |
| SCHEMBL28078513 | 0.81 | MEN1 (0.49) | KDM4EALDH1A1TDP1GABRA1GABRG2 | |
| SCHEMBL28078523 | 0.81 | PDE5A (0.39) | GFERKDM4EALDH1A1PTPN11MAPT | |
| SCHEMBL28931713 | 0.80 | MEN1 (0.58) | GFERKDM4EALDH1A1TDP1GABRA1 | |
| SCHEMBL28032234 | 0.80 | MEN1 (0.45) | KDM4EALDH1A1PTPN11GABRA1GABRG2 | |
| SCHEMBL28031775 | 0.79 | TP53 (0.45) | GFERKDM4EALDH1A1PTPN11GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105017126-B | Perfluoroalkyl azole derivatives and its synthetic method | 上海麦克林生化科技有限公司 | 2018-01-19 | — | — | CN | disclosed |
| CN-105017126-A | Perfluoroalkyl pyrrole derivative and synthesis method thereof | UNIV SHANGHAI | 2015-11-04 | — | — | CN | disclosed |