Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 8/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL851200 | 0.97 | — | — | |
| SCHEMBL383296 | 0.83 | — | — | |
| SCHEMBL3899146 | 0.81 | EPHX1 (0.67) | ACHEEPHX1ALDH1A1 | |
| SCHEMBL11527890 | 0.79 | EPHX1 (0.70) | ACHEEPHX1 | |
| SCHEMBL3899906 | 0.79 | EPHX1 (0.70) | ACHEEPHX1 | |
| SCHEMBL2454206 | 0.79 | EPHX1 (0.70) | ACHEEPHX1 | |
| SCHEMBL13412671 | 0.79 | EPHX1 (0.70) | ACHEEPHX1 | |
| SCHEMBL11528808 | 0.79 | EPHX1 (0.70) | ACHEEPHX1 | |
| SCHEMBL2912153 | 0.79 | ACHE (0.48) | KDM4EGLAACHEEPHX1ALDH1A1 | |
| SCHEMBL2656053 | 0.79 | ACHE (0.48) | KDM4EGLAACHEEPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105018541-A | Synthetic method of (S)-t-butyl-2-hydroxypropylcarbamate | SHANGHAI SYNTHEALL PHARMACEUTICALS RES CO LTD | 2015-11-04 | — | — | CN | claimed |
| CN-105018541-A | Synthetic method of (S)-t-butyl-2-hydroxypropylcarbamate | SHANGHAI SYNTHEALL PHARMACEUTICALS RES CO LTD | 2015-11-04 | — | — | CN | disclosed |