Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21077348 | 0.87 | ACHE (0.43) | ACHEKDM4EGLAEPHX1ALDH1A1 | |
| SCHEMBL27393398 | 0.87 | ACHE (0.43) | ACHEKDM4EGLAEPHX1ALDH1A1 | |
| SCHEMBL2184403 | 0.85 | SMN1; SMN2 (0.47) | ACHEKDM4EGLAEPHX1ALDH1A1 | |
| SCHEMBL590532 | 0.84 | EPHX1 (0.59) | ACHEEPHX1ALDH1A1HPGD | |
| SCHEMBL6136635 | 0.84 | HPGD (0.43) | ACHEKDM4EGLAEPHX1ALDH1A1 | |
| SCHEMBL9842283 | 0.84 | ACHE (0.41) | ACHEKDM4EGLAEPHX1ALDH1A1 | |
| SCHEMBL2656053 | 0.83 | ACHE (0.48) | ACHEKDM4EGLAEPHX1ALDH1A1 | |
| SCHEMBL5138408 | 0.82 | EPHX1 (0.69) | ACHEEPHX1ALDH1A1 | |
| SCHEMBL20711249 | 0.82 | MAPK1 (0.40) | ACHEKDM4EGLAEPHX1ALDH1A1 | |
| SCHEMBL27727591 | 0.82 | KDM4E (0.40) | ACHEKDM4EGLAEPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3421454-B9 | PIPERIDINE DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2023-08-09 | — | — | EP | disclosed |
| EP-3421454-B1 | PIPERIDINE DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2023-04-05 | — | — | EP | disclosed |
| CN-108884044-B | Piperidine derivatives | 大塚制药株式会社 | 2023-01-31 | — | — | CN | disclosed |
| US-11078181-B2 | Diaryl pyrazole compound and formulation for controlling harmful organisms | NIPPON SODA CO., LTD. (JP) | 2021-08-03 | — | — | US | disclosed |
| EP-3556751-B1 | DIARYLPYRAZOLE COMPOUND AND PEST CONTROL AGENT | NIPPON SODA CO (JP) | 2021-04-28 | — | — | EP | disclosed |
| US-10851079-B2 | Piperidine derivative | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-12-01 | — | — | US | disclosed |
| EP-3556751-A1 | DIARYLPYRAZOLE COMPOUND AND PEST CONTROL AGENT | Nippon Soda Co., Ltd. (JP) | 2019-10-23 | — | — | EP | disclosed |
| US-20190040039-A1 | PIPERIDINE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2019-02-07 | — | — | US | disclosed |
| EP-3421454-A1 | PIPERIDINE DERIVATIVE | Otsuka Pharmaceutical Co., Ltd. (JP) | 2019-01-02 | — | — | EP | disclosed |
| EP-2223929-A1 | GAMBOGIC GLYCOSIDE DERIVATIVES AND ANALOGS, THE PREPARATION AND THE APPLICATION THEREOF | Liaoning Lifeng Scientific&Technology Development Company Ltd. (CN) | 2010-09-01 | — | — | EP | disclosed |
| US-4205169-A | N-[4-Azido-5-(2-ethoxyethyl)-6-phenyl-2-pyrimidinyl]acetamide and congeners | G. D. SEARLE & CO. (US) | 1980-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078181-B2 | Diaryl pyrazole compound and formulation for controlling harmful organisms | RABL3, CTRL, L3MBTL3 | ACHE 142/4885KDM4E 3364/4885GLA 3322/4885 |
| US-10851079-B2 | Piperidine derivative | EP300, SLC11A2, TBC1D5 | ACHE 2573/4885KDM4E 1265/4885GLA 3368/4885 |
| US-20190040039-A1 | PIPERIDINE DERIVATIVE | EP300, SLC11A2, TBC1D5 | ACHE 2573/4885KDM4E 1265/4885GLA 3368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.