SCHEMBL28032383

SCHEMBL28032383

Cn1c2cc(N)ccc2c2ccc(Br)cc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
KDM4E B2RXH2 2/20 0.45
MAPT P10636 2/20 0.45
PDGFRA P16234 1/20 0.41
CDK5 Q00535 1/20 0.41
TYRO3 Q06418 1/20 0.41
MAPK1 P28482 2/20 0.39
ALOX15 P16050 1/20 0.39
PABPC1 P11940 1/20 0.39
ACHE P22303 1/20 0.38
TLR9 Q9NR96 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
EGLN1 Q9GZT9 2/20 0.38
CCNB2 O95067 1/20 0.37
CDK1 P06493 1/20 0.37
CCNB1 P14635 1/20 0.37
CCNB3 Q8WWL7 1/20 0.37
BRPF1 P55201 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29556288 0.88 GPR3 (0.44) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL3872734 0.88 GPR3 (0.44) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL3281839 0.88 GPR3 (0.44) ALDH1A1MEN1KMT2AKDM4EMAPT
Hydrochloric Acid SCHEMBL19896390 0.86 MEN1 (0.42) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL5014769 0.84 ACHE (0.41) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL10871998 0.81 MAPT (0.45) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL13374193 0.78 ALDH1A1 (0.41) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL3875050 0.78 GPR3 (0.64) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL20221051 0.78 ACHE (0.41) ALDH1A1MEN1KMT2AKDM4EMAPT
SCHEMBL8011931 0.78 GPR3 (0.64) ALDH1A1MEN1KMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104892634-A Carbazole dioxazine compound INST CHEMISTRY CO LTD HENAN ACADEMY OF SCIENCES 2015-09-09 CN disclosed