Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL150072 | 0.81 | FDPS (0.41) | FDPSSMPD1MEN1MAPTKMT2A | |
| SCHEMBL2239348 | 0.80 | FDPS (0.40) | FDPSSMPD1GGPS1 | |
| Hydrochloric Acid SCHEMBL2418361 | 0.80 | FDPS (0.40) | FDPSSMPD1MEN1MAPTKMT2A | |
| SCHEMBL10706328 | 0.80 | SMPD1 (0.43) | FDPSSMPD1MEN1MAPTKMT2A | |
| SCHEMBL29087510 | 0.80 | SMPD1 (0.43) | FDPSSMPD1MEN1MAPTKMT2A | |
| SCHEMBL31319781 | 0.77 | DGAT1 (0.39) | FDPSSMPD1MEN1MAPTKMT2A | |
| SCHEMBL17756699 | 0.77 | CYP4F2 (0.47) | FDPSSMPD1MEN1MAPTKMT2A | |
| SCHEMBL17768312 | 0.76 | SMPD1 (0.40) | FDPSSMPD1MEN1MAPTKMT2A | |
| SCHEMBL4825036 | 0.76 | SMPD1 (0.40) | FDPSSMPD1MEN1MAPTKMT2A | |
| SCHEMBL29762781 | 0.76 | SMPD1 (0.40) | FDPSSMPD1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113908291-A | Method for producing immunoligand/effector molecule conjugates by sequence-specific transpeptidases | 恩比伊治疗股份公司 | 2022-01-11 | — | — | CN | disclosed |
| CN-105142675-B | Method for producing immunoligand/effector molecule conjugates by sequence-specific transpeptidases | 恩比伊治疗股份公司 | 2021-08-20 | — | — | CN | disclosed |
| CN-103153345-B | Amatoxin conjugates with improved linkers | 海德堡医药有限责任公司 | 2016-08-10 | — | — | CN | disclosed |
| CN-103442736-B | Amatoxin conjugates with improved bonding | HEIDELBERG PHARMA GMBH (DE) | 2015-09-30 | — | — | CN | disclosed |