Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.54 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016009 | 0.85 | TNKS2 (0.47) | POLBCYP1A2CYP2D6PARP1 | |
| SCHEMBL6016018 | 0.78 | KDM4E (0.55) | SIGMAR1KCNH2CYP1A2HRH3 | |
| SCHEMBL27601537 | 0.76 | SLC6A2 (0.38) | SIGMAR1CYP2D6SLC6A4 | |
| SCHEMBL6015810 | 0.73 | ALDH1A1 (0.60) | POLBCYP2D6 | |
| SCHEMBL6016002 | 0.73 | ATM (0.58) | CYP1A2HRH3 | |
| SCHEMBL6015767 | 0.73 | POLB (0.60) | POLBKCNH2CYP1A2CYP2D6PARP1 | |
| SCHEMBL6015785 | 0.70 | ALDH1A1 (0.55) | SIGMAR1KCNH2CYP1A2HRH3PARP1 | |
| SCHEMBL15987537 | 0.70 | SIGMAR1 (0.56) | SIGMAR1L3MBTL3POLBKCNJ1KCNH2 | |
| SCHEMBL3176117 | 0.69 | SIGMAR1 (0.63) | SIGMAR1L3MBTL3POLBCYP1A2CYP2D6 | |
| SCHEMBL3186832 | 0.69 | SIGMAR1 (0.55) | SIGMAR1L3MBTL3POLBCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104936596-A | Neuroprotective CB2 receptor agonists | CLEVELAND CLINIC FOUNDATION | 2015-09-23 | — | — | CN | disclosed |