SCHEMBL28032637

SCHEMBL28032637

CC(CC(=O)O)C1=NOC(c2ccccc2)(c2ccccc2)C1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.38
ADAMTS4 O75173 1/20 0.34
APOBEC3A P31941 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
SLC22A12 Q96S37 1/20 0.33
ALDH1A1 P00352 3/20 0.33
CHRM2 P08172 3/20 0.32
CHRM4 P08173 3/20 0.32
CHRM5 P08912 3/20 0.32
CHRM1 P11229 3/20 0.32
CHRM3 P20309 3/20 0.32
GLA P06280 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TSHR P16473 1/20 0.32
OPRM1 P35372 1/20 0.32
OPRL1 P41146 1/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.32
SLC6A2 P23975 1/20 0.32
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopropylamine SCHEMBL28970090 0.71 ALDH1A1 (0.34) ALDH1A1CHRM2CHRM4CHRM5CHRM1
SCHEMBL29216618 0.69 PDCD1 (0.41) ALDH1A1SMN1; SMN2TSHRKMT2A
SCHEMBL27935385 0.69
SCHEMBL135288 0.69 AKR1C1 (0.35) ALDH1A1CHRM2CHRM4CHRM5CHRM1
SCHEMBL6578687 0.68 HSD17B10 (0.39) ALDH1A1SMN1; SMN2TSHROPRM1OPRL1
SCHEMBL28044294 0.68 SMN1; SMN2 (0.44) FFAR1ALDH1A1SMN1; SMN2PTGDR2
SCHEMBL28574647 0.67 POLB (0.35) ALDH1A1CHRM2CHRM4CHRM5CHRM1
SCHEMBL167559 0.67 AKR1C1 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL29498824 0.67 LDHA (0.36) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL7640011 0.67 MAPT (0.47) ALDH1A1GLASMN1; SMN2TSHROPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105592699-B Herbicide-safener combination containing N- (1,3, 4-oxadiazol-2-yl) arylcarboxylic acid amides 拜耳作物科学股份公司 2019-06-14 CN disclosed
CN-102264226-B Bicyclooctane-1, the 3-derovatives of phenyl-replacement BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-12-16 CN disclosed
CN-105028414-A HERBICIDE-SAFENER COMBINATION BAYER IP GMBH 2015-11-11 CN disclosed