SCHEMBL28032996

SCHEMBL28032996

O=C(O)C(F)Oc1ccc(Cl)cc1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.54
PPARA Q07869 20/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3559428 0.81 CYP1A2 (0.46) PPARGPPARA
SCHEMBL5925159 0.81 PPARG (0.59) PPARGPPARA
SCHEMBL25564630 0.80 LDHA (0.46) PPARGPPARA
SCHEMBL1163280 0.80 PARP10 (0.41) PPARGPPARA
SCHEMBL503845 0.79 PPARG (0.58) PPARGPPARA
SCHEMBL5711742 0.79 LDHA (0.64) PPARGPPARA
SCHEMBL6232699 0.78 CYP3A4 (0.51) PPARGPPARA
SCHEMBL28904037 0.78 ALDH1A1 (0.49) PPARGPPARA
SCHEMBL11725605 0.78 PPARG (0.56) PPARGPPARA
SCHEMBL367795 0.78 PPARG (0.56) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103288772-B There are 2,4,5-polysubstituted thiazole derivative and preparations thereof of weeding activity HUAZHONG NORMAL UNIVERSITY (CN) 2015-10-14 CN disclosed