Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 4/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.39 |
| ▸ | HTR3B | O95264 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL349915 | 0.81 | MAPT (0.46) | SIGMAR1ALDH1A1TSHRHSD17B10LMNA | |
| Tert-Butyl Formate SCHEMBL27576636 | 0.79 | ADRB1 (0.47) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL351169 | 0.77 | MAPT (0.60) | ALDH1A1TSHRLMNAGPR119MAPT | |
| SCHEMBL349139 | 0.77 | NPSR1 (0.47) | SIGMAR1ALDH1A1TSHRLMNAGPR119 | |
| Tert-Butyl Formate SCHEMBL28675132 | 0.76 | TRIM24 (0.51) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Tert-Butyl Formate SCHEMBL27859337 | 0.76 | ADRB1 (0.47) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Tert-Butyl Formate SCHEMBL27615062 | 0.76 | ADRB1 (0.47) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Tert-Butyl Formate SCHEMBL28331831 | 0.76 | ADRB1 (0.47) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Tert-Butyl Formate SCHEMBL27605765 | 0.76 | LTA4H (0.59) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Tert-Butyl Formate SCHEMBL27908417 | 0.76 | ALDH1A1 (0.52) | ADRB1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101001842-B | Amido compounds and the application as medicine thereof | INCYTE CORP. (US) | 2015-10-07 | — | — | CN | disclosed |