Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | GCK | P35557 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27569231 | 0.86 | PARP10 (0.51) | MAPTNPC1RAB9ACXCL8MAPK8 | |
| SCHEMBL8343982 | 0.85 | CARM1 (0.52) | MAPTHTR1ASLC6A2SLC6A4TRPA1 | |
| Hydrochloric Acid SCHEMBL8725899 | 0.80 | P2RY1 (0.48) | HTR1ASLC6A2SLC6A4MRGPRX1MRGPRX4 | |
| SCHEMBL28822437 | 0.78 | MAPT (0.46) | MAPTNPC1RAB9ACXCL8MAPK8 | |
| SCHEMBL28822439 | 0.78 | CXCL8 (0.56) | MAPTNPC1RAB9ACXCL8MAPK8 | |
| SCHEMBL28035897 | 0.78 | KMT2A (0.47) | KDM4EKMT2ASMN1; SMN2TRPA1PTGER4 | |
| SCHEMBL11924511 | 0.73 | MAPK8 (0.54) | MAPTNPC1RAB9ACXCL8MAPK8 | |
| SCHEMBL5523941 | 0.73 | MAPK8 (0.57) | MAPTNPC1RAB9AMAPK8HTR1A | |
| SCHEMBL30693359 | 0.73 | MAPK8 (0.57) | MAPTNPC1RAB9AMAPK8HTR1A | |
| SCHEMBL28030562 | 0.73 | HAO1 (0.45) | KDM4EKMT2AMRGPRX1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104961691-A | Preparation method of 3-(2-fluorophenoxy) pyrazine-2-carboxylic acid | CHANGSHA SHENCHENG BIOTECHNOLOGY CO LTD | 2015-10-07 | — | — | CN | claimed |
| CN-104961691-A | Preparation method of 3-(2-fluorophenoxy) pyrazine-2-carboxylic acid | CHANGSHA SHENCHENG BIOTECHNOLOGY CO LTD | 2015-10-07 | — | — | CN | disclosed |
| CN-104961691-A | Preparation method of 3-(2-fluorophenoxy) pyrazine-2-carboxylic acid | CHANGSHA SHENCHENG BIOTECHNOLOGY CO LTD | 2015-10-07 | — | — | CN | disclosed |
| CN-104961691-A | Preparation method of 3-(2-fluorophenoxy) pyrazine-2-carboxylic acid | CHANGSHA SHENCHENG BIOTECHNOLOGY CO LTD | 2015-10-07 | — | — | CN | disclosed |