Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL721024 | 0.84 | HTR6 (0.46) | HTR6 | |
| SCHEMBL12066718 | 0.82 | PTPN11 (0.51) | HTR6 | |
| SCHEMBL8944259 | 0.81 | L3MBTL1 (0.67) | HTR6L3MBTL1 | |
| SCHEMBL28149181 | 0.80 | L3MBTL1 (0.53) | HTR6L3MBTL1 | |
| SCHEMBL1906556 | 0.79 | L3MBTL1 (0.51) | HTR6L3MBTL1 | |
| SCHEMBL12066713 | 0.79 | TNIK (0.47) | HTR6 | |
| SCHEMBL30280532 | 0.77 | HTR6 (0.44) | HTR6L3MBTL1 | |
| SCHEMBL28822389 | 0.77 | HTR6 (0.50) | HTR6 | |
| SCHEMBL1666756 | 0.76 | L3MBTL1 (0.48) | HTR6L3MBTL1 | |
| SCHEMBL20292779 | 0.75 | L3MBTL1 (0.53) | HTR6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104884059-A | Mixed lineage kinase inhibitors for hiv/aids therapies | UNIV ROCHESTER | 2015-09-02 | — | — | CN | disclosed |