SCHEMBL28033181

SCHEMBL28033181

CC(=O)n1c(Cl)cc2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.50
NOTUM Q6P988 1/20 0.46
ALDH1A1 P00352 3/20 0.44
KDM4E B2RXH2 2/20 0.44
HPGD P15428 2/20 0.44
HSD17B10 Q99714 2/20 0.44
MAPT P10636 1/20 0.44
TSHR P16473 1/20 0.44
MCL1 Q07820 1/20 0.43
KDR P35968 4/20 0.42
PDGFRB P09619 3/20 0.42
TUBB4A P04350 2/20 0.42
TUBB P07437 2/20 0.42
TUBA3C P0DPH7 2/20 0.42
TUBA1B P68363 2/20 0.42
TUBA4A P68366 2/20 0.42
TUBB4B P68371 2/20 0.42
TUBB3 Q13509 2/20 0.42
TUBB2A Q13885 2/20 0.42
TUBB8 Q3ZCM7 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27597857 0.85 KDR (0.51) MCL1KDRPDGFRBDAOSLC9A1
SCHEMBL3842692 0.83 DAO (0.46) ALDH1A1KDM4EHPGDHSD17B10TSHR
SCHEMBL28548039 0.79 POLB (0.52) POLBNOTUMALDH1A1KDM4EHPGD
SCHEMBL17022579 0.79 POLB (0.52) POLBNOTUMALDH1A1KDM4EHPGD
SCHEMBL13940630 0.79 ALDH1A1 (0.60) POLBALDH1A1KDM4EHPGDHSD17B10
SCHEMBL6072599 0.78 POLB (0.50) POLBNOTUMALDH1A1KDM4EHPGD
SCHEMBL1697448 0.78 POLB (0.50) POLBNOTUMALDH1A1KDM4EHPGD
SCHEMBL4125402 0.77 NR1H2 (0.60)
SCHEMBL4222282 0.76 MCL1 (0.64) POLBNOTUMALDH1A1KDM4EHPGD
SCHEMBL6208706 0.75 POLB (0.47) POLBNOTUMALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102958584-B Filter plate article with water absorbent filter assembly 3M INNOVATIVE PROPERTIES CO. (US) 2015-10-21 CN disclosed