Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.40 |
| ▸ | TUBB | P07437 | 2/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17075022 | 0.81 | L3MBTL1 (0.47) | POLBMTNR1AMTNR1BMCL1L3MBTL1 | |
| SCHEMBL28548039 | 0.79 | POLB (0.52) | POLBNOTUMMCL1NPC1RAB9A | |
| SCHEMBL17022579 | 0.79 | POLB (0.52) | POLBNOTUMMCL1NPC1RAB9A | |
| SCHEMBL28033181 | 0.78 | POLB (0.50) | POLBNOTUMMCL1NPC1RAB9A | |
| SCHEMBL6072599 | 0.78 | POLB (0.50) | POLBNOTUMMCL1NPC1RAB9A | |
| SCHEMBL23168121 | 0.77 | POLB (0.46) | POLBNOTUMMCL1NPC1RAB9A | |
| SCHEMBL5599682 | 0.77 | NR1H2 (0.56) | — | |
| SCHEMBL4222282 | 0.76 | MCL1 (0.64) | POLBNOTUMMCL1KDM4EALDH1A1 | |
| SCHEMBL6208706 | 0.75 | POLB (0.47) | POLBNOTUMMCL1NPC1RAB9A | |
| SCHEMBL13940630 | 0.75 | ALDH1A1 (0.60) | POLBMTNR1AMTNR1BL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004811-A1 | PROCESS FOR THE PREPARATION OF 5-SUBSTSITUTED INDOLE DERIVATIVE | IND-SWIFT LABORATORIES LIMITED (IN) | 2012-01-12 | — | — | WO | disclosed |