Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.64 |
| ▸ | DAO | P14920 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CCR2 | P41597 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14398966 | 0.86 | MCL1 (0.60) | MCL1DAOALDH1A1TSHRCCR2 | |
| SCHEMBL29780995 | 0.85 | DAO (0.65) | MCL1DAOALDH1A1TSHRCCR2 | |
| SCHEMBL3638561 | 0.85 | DAO (0.65) | MCL1DAOALDH1A1TSHRCCR2 | |
| SCHEMBL6988076 | 0.81 | MCL1 (0.58) | MCL1DAOALDH1A1TSHRCCR2 | |
| SCHEMBL9514581 | 0.81 | DAO (0.59) | MCL1DAOALDH1A1TSHRCCR2 | |
| SCHEMBL10955359 | 0.79 | CCR9 (0.49) | MCL1DAOALDH1A1TSHRCCR2 | |
| SCHEMBL6407386 | 0.78 | CCR2 (0.52) | MCL1ALDH1A1CCR2KDM4EHPGD | |
| SCHEMBL16627573 | 0.78 | MCL1 (0.46) | MCL1DAOALDH1A1TSHRCCR2 | |
| SCHEMBL117186 | 0.78 | MCL1 (1.00) | MCL1DAOALDH1A1TSHRCCR2 | |
| SCHEMBL28548039 | 0.78 | POLB (0.52) | MCL1DAOALDH1A1TSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112375028-A | Method for synthesizing (2S) -indoline-formic acid | 安徽美诺华药物化学有限公司 | 2021-02-19 | — | — | CN | claimed |
| CN-112375028-A | Method for synthesizing (2S) -indoline-formic acid | 安徽美诺华药物化学有限公司 | 2021-02-19 | — | — | CN | disclosed |
| US-20090028796-A1 | PESTICIDAL COMPOSITION COMPRISING INDOLE DERIVATES | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e. V. (DE) | 2009-01-29 | — | — | US | disclosed |
| EP-1497282-A2 | INHIBITORS OF SERINE PROTEASE, PARTICULARLY HEPATITIS C VIRUS NS3-NS4 PROTEASE | Vertex Pharmaceuticals Incorporated (US) | 2005-01-19 | — | — | EP | disclosed |
| EP-0937714-B1 | Process for the preparation of an optically active indoline-2-carboxylic acid or derivative thereof | DSM IP ASSETS BV (NL) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003087092-A2 | INHIBITORS OF SERINE PROTEASES, PARTICULARLY HEPATITIS C VIRUS NS3 - NS4 PROTEASE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2003-10-23 | — | — | WO | disclosed |
| US-6121460-A | Process for the preparation of an optically active indoline-2-carboxylic acid or derivative thereof | DSM N.V. (NL) | 2000-09-19 | — | — | US | disclosed |
| EP-0937714-A1 | Process for the preparation of an optically active indoline-2-carboxylic acid or derivative thereof | DSM N.V. (NL) | 1999-08-25 | — | — | EP | disclosed |
| US-5656648-A | TREATMENT OF PATHOLOGIES NECESSITATING STIMULATION OF CHOLECYSTOKININ-A RECEPTORS BY TOTAL OR PARTIAL AGONIST EFFECT | SANOFI (FR) | 1997-08-12 | — | — | US | disclosed |
| CN-1107158-A | Polysubstituted 2-amino-thiazole derivatives | SANOFI ELF (FR) | 1995-08-23 | — | — | CN | disclosed |
| US-5314889-A | Hormone antagonists | ELF SANOFI (FR) | 1994-05-24 | — | — | US | disclosed |
| EP-0273418-B1 | Heat-sensitive recording material using chromeno compound | KANZAKI PAPER MFG CO LTD (JP) | 1993-11-24 | — | — | EP | disclosed |
| EP-0249885-B1 | HEAT-SENSITIVE RECORDING MATERIAL | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1992-01-02 | — | — | EP | disclosed |
| EP-0234540-B1 | HEAT-SENSITIVE RECORDING MATERIAL | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1991-10-16 | — | — | EP | disclosed |
| US-4803193-A | COLORFASTNESS; READABLE BY OPTICAL CHARACTER-READING DEVICES | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1989-02-07 | — | — | US | disclosed |
| US-4794101-A | MIXTURE OF PHTHALIDE DYE, FLUORAN COMPOUND AND POLYVALENT METAL SALT OF AN AROMATIC CARBOXYLIC ACID | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1988-12-27 | — | — | US | disclosed |
| EP-0273418-A2 | Heat-sensitive recording material using chromeno compound | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1988-07-06 | — | — | EP | disclosed |
| US-4731353-A | METAL SALT OF INDOLE-2-CARBOXYLIC ACID COLOR DEVELOPER | KANZAKI PAPER MANUFACTURING COMPANY, LIMITED (JP) | 1988-03-15 | — | — | US | disclosed |
| EP-0249885-A2 | Heat-sensitive recording material | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1987-12-23 | — | — | EP | disclosed |
| EP-0234540-A2 | Heat-sensitive recording material | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1987-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090028796-A1 | PESTICIDAL COMPOSITION COMPRISING INDOLE DERIVATES | IDO1, IDO2, INMT | MCL1 2088/4885DAO 237/4885ALDH1A1 2643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.