Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SI | P14410 | 1/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP8 | P22894 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396940 | 0.80 | APP (0.72) | PKMMGAMGAASIMGAM2 | |
| SCHEMBL27462009 | 0.78 | MGAM (0.48) | PKMMGAMGAASIMGAM2 | |
| SCHEMBL900790 | 0.77 | ALDH1A1 (0.56) | PKMGAAMAPTALDH1A1TDP1 | |
| SCHEMBL219670 | 0.76 | BCHE (0.55) | PKMMGAMGAASIMGAM2 | |
| SCHEMBL28033417 | 0.76 | ALDH1A1 (0.49) | PKMGAAMAPTALDH1A1TDP1 | |
| SCHEMBL5065477 | 0.76 | PKM (0.48) | PKMMGAMGAASIMGAM2 | |
| SCHEMBL10339419 | 0.75 | MGAM (0.58) | PKMMGAMGAASIMGAM2 | |
| SCHEMBL220051 | 0.73 | APP (0.51) | PKMMGAMGAASIMGAM2 | |
| SCHEMBL8866822 | 0.73 | RAB9A (0.72) | PKMMGAMGAASIMGAM2 | |
| SCHEMBL218866 | 0.73 | APP (0.51) | PKMMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104987350-A | Chiral alpha-amino phosphonate ester compounds having anti-virus activity and containing benzothiazole heterocycle, preparation and applications thereof | UNIV GUIZHOU | 2015-10-21 | — | — | CN | disclosed |