SCHEMBL28033465

SCHEMBL28033465

O=C(CI)CC(=O)OCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
MAPK1 P28482 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
TDP1 Q9NUW8 2/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A3 Q01959 1/20 0.50
KMT2A Q03164 1/20 0.50
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HCAR2 Q8TDS4 1/20 0.46
CDC25B P30305 1/20 0.45
CA12 O43570 2/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA9 Q16790 2/20 0.45
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
POLB P06746 1/20 0.44
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1011103 0.89 ALDH1A1 (0.68) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL5396492 0.87 ALDH1A1 (0.72) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL4413332 0.85 ALDH1A1 (0.68) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL294341 0.85 ALDH1A1 (0.73) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL8069055 0.83 ALDH1A1 (0.70) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL5413781 0.82 ALDH1A1 (0.59) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL4486830 0.82 ALDH1A1 (0.59) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL4503978 0.82 ALDH1A1 (0.59) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL21424841 0.81 ALDH1A1 (0.63) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2
SCHEMBL29152109 0.81 ALDH1A1 (0.54) ALDH1A1MAPK1L3MBTL1TDP1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105061338-A 3-methyl-quinoxaline-2-carboxylic acid chemical synthesis method based on ionic liquid system PINGYUAN WEIFENG YONGZHU TECHNOLOGY CO LTD 2015-11-18 CN claimed
CN-105061338-A 3-methyl-quinoxaline-2-carboxylic acid chemical synthesis method based on ionic liquid system PINGYUAN WEIFENG YONGZHU TECHNOLOGY CO LTD 2015-11-18 CN disclosed