Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.52 |
| ▸ | CDC25B | P30305 | 1/20 | 0.50 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1834864 | 0.85 | ALDH1A1 (0.70) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL28033465 | 0.85 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL9840777 | 0.84 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL1177836 | 0.83 | ALDH1A1 (0.73) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL294341 | 0.83 | ALDH1A1 (0.73) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL22279481 | 0.82 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1KMT2ASMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL28215437 | 0.82 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL3727214 | 0.82 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL8892351 | 0.82 | ALDH1A1 (0.66) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 | |
| SCHEMBL7696360 | 0.81 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1TDP1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111386257-B | Process for preparing enzalutamide using novel intermediates | 阿尔第药物实验室有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-113717548-B | Surface-modified silica gel and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-10-11 | — | — | CN | claimed |
| EP-3733648-B1 | METHOD FOR PREPARING 5R-BENZYLOXYAMINOPIPERIDIN-2S-CARBOXYLIC ACID OR DERIVATIVE THEREOF | XINFA PHARMACEUTICAL CO LTD (CN) | 2022-06-08 | — | — | EP | claimed |
| CN-113717548-A | Surface-modified silica gel and preparation method and application thereof | 中国石油化工股份有限公司 | 2021-11-30 | — | — | CN | claimed |
| US-20210323920-A1 | METHOD OF PREPARING 5R-[(BENZYLOXY) AMINO] PIPERIDINE-2S-CARBOXYLIC ACID OR A DERIVATIVE THEREOF | XINFA PHARMACEUTICAL CO., LTD (CN) | 2021-10-21 | — | — | US | claimed |
| US-11142499-B1 | Method of preparing 5R-[(benzyloxy) amino] piperidine-2S-carboxylic acid or a derivative thereof | XINFA PHARMACEUTICAL CO., LTD (CN) | 2021-10-12 | — | — | US | claimed |
| CN-113461591-A | Preparation method of precursor raw material Pht-AEEA-AEEA for side chain of Somalutide | 浙江泽瑞生物医药有限公司 | 2021-10-01 | — | — | CN | claimed |
| CN-109970625-B | Preparation method of 5R-benzyloxyaminopiperidine-2S-formic acid or derivative thereof | 新发药业有限公司 | 2021-02-26 | — | — | CN | claimed |
| EP-3733648-A1 | METHOD FOR PREPARING 5R-BENZYLOXYAMINOPIPERIDIN-2S-CARBOXYLIC ACID OR DERIVATIVE THEREOF | Xinfa Pharmaceutical Co., Ltd (CN) | 2020-11-04 | — | — | EP | claimed |
| CN-111386257-A | Process for preparing enzalutamide using novel intermediates | 阿尔第实业有限公司 | 2020-07-07 | — | — | CN | claimed |
| CN-110078644-B | preparation method of [2- [1- (Fmoc-amino) ethoxy ] acetic acid | 深圳市茵诺圣生物科技有限公司 | 2019-12-17 | — | — | CN | claimed |
| CN-110078644-A | A kind of preparation method of [2- [1- (Fmoc- amino) ethyoxyl] ethyoxyl] acetic acid | 深圳市茵诺圣生物科技有限公司 | 2019-08-02 | — | — | CN | claimed |
| CN-109970625-A | A kind of preparation method of 5R- benzyloxy amino piperidine -2S- formic acid or derivatives thereof | 新发药业有限公司 | 2019-07-05 | — | — | CN | claimed |
| CN-111386257-B | Process for preparing enzalutamide using novel intermediates | 阿尔第药物实验室有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-113717548-B | Surface-modified silica gel and preparation method and application thereof | 中国石油化工股份有限公司 | 2022-10-11 | — | — | CN | disclosed |
| US-20220274954-A1 | SUBSTITUTED N-PHENYL-N-AMINOUARCILS AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-09-01 | — | — | US | disclosed |
| US-4629787-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | MERCK & CO., INC. (US) | 1986-12-16 | — | — | US | disclosed |
| EP-0179428-A2 | Indoleacetic acid derivative and a pharmaceutical preparation | GREEN CROSS CORPORATION (JP) | 1986-04-30 | — | — | EP | disclosed |
| EP-0046291-B1 | SUBSTITUTED CAPROLACTAM DERIVATIVES AS ANTIHYPERTENSIVES, PROCESS FOR PREPARING THEM, PHARMACEUTICAL COMPOSITION CONTAINING THEM, AND INTERMEDIATES | MERCK & CO. INC. (US) | 1985-12-27 | — | — | EP | disclosed |
| EP-0046291-A2 | Substituted caprolactam derivatives as antihypertensives, process for preparing them, pharmaceutical composition containing them, and intermediates | MERCK & CO. INC. (US) | 1982-02-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11142499-B1 | Method of preparing 5R-[(benzyloxy) amino] piperidine-2S-carboxylic acid or a derivative thereof | GLUL, GRIN2D, GRIN2C | ALDH1A1 221/4885MAPK1 4715/4885L3MBTL1 4184/4885 |
| US-20220274954-A1 | SUBSTITUTED N-PHENYL-N-AMINOUARCILS AND SALTS THEREOF AND USE THEREOF AS HERBICIDAL AGENTS | DDC, ABAT, NPEPPS | ALDH1A1 487/4885MAPK1 2206/4885L3MBTL1 848/4885 |
| US-20210323920-A1 | METHOD OF PREPARING 5R-[(BENZYLOXY) AMINO] PIPERIDINE-2S-CARBOXYLIC ACID OR A DERIVATIVE THEREOF | GLUL, GRIN2D, GRIN2C | ALDH1A1 221/4885MAPK1 4715/4885L3MBTL1 4184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.