SCHEMBL28033478

SCHEMBL28033478

CCCCC(CC)Cc1ccc2cc(O)c(SC)cc2c1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
BDKRB2 P30411 3/20 0.40
LMNA P02545 2/20 0.33
TAS1R3 Q7RTX0 1/20 0.32
TAS1R1 Q7RTX1 1/20 0.32
ALDH1A1 P00352 3/20 0.32
PPARA Q07869 1/20 0.32
CA2 P00918 1/20 0.31
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28033421 0.83 BDKRB2 (0.38) BDKRB2
SCHEMBL3731371 0.82 BDKRB2 (0.51) BDKRB2ALDH1A1CA2CYP3A4TSHR
SCHEMBL3723663 0.82 BDKRB2 (0.51) BDKRB2ALDH1A1CA2CYP3A4TSHR
SCHEMBL14782808 0.79 KAT8 (0.48) LMNAALDH1A1PPARACYP3A4
SCHEMBL16672060 0.79 KAT8 (0.48) LMNAALDH1A1PPARACYP3A4
SCHEMBL14783476 0.79 KAT8 (0.48) LMNAALDH1A1PPARACYP3A4
SCHEMBL6656944 0.78 BDKRB2 (0.47) BDKRB2ALDH1A1CA2CYP3A4
SCHEMBL15301082 0.78 BDKRB2 (0.47) BDKRB2ALDH1A1CA2CYP3A4
SCHEMBL27749627 0.75 ALOX15 (0.53) LMNAALDH1A1CA2CYP3A4TSHR
SCHEMBL14353644 0.73 BDKRB2 (0.56) BDKRB2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104956508-A ORGANIC SEMICONDUCTOR MATERIAL FOR SOLUTION PROCESS AND ORGANIC SEMICONDUCTOR DEVICE NIPPON KAYAKU KK 2015-09-30 CN disclosed