Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.66 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.50 |
| ▸ | ERN1 | O75460 | 3/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15256767 | 0.93 | ALDH1A1 (0.66) | ALDH1A1TRIM24TYRTRIM33CYP1A2 | |
| SCHEMBL172939 | 0.80 | ALDH1A1 (0.71) | ALDH1A1TRIM24TYRTRIM33CYP1A2 | |
| SCHEMBL29392394 | 0.80 | ALDH1A1 (0.71) | ALDH1A1TRIM24TYRTRIM33CYP1A2 | |
| SCHEMBL96291 | 0.80 | ALDH1A1 (1.00) | ALDH1A1TRIM24TYRTRIM33CYP1A2 | |
| SCHEMBL29708066 | 0.78 | MAPT (0.54) | ALDH1A1MAPTKDM4EERN1MEN1 | |
| SCHEMBL545661 | 0.78 | MAPT (0.54) | ALDH1A1MAPTKDM4EERN1MEN1 | |
| Hydrochloric Acid SCHEMBL9456784 | 0.78 | ALDH1A1 (0.96) | ALDH1A1TRIM24TYRTRIM33CYP1A2 | |
| SCHEMBL590873 | 0.78 | KDM4E (0.68) | ALDH1A1TRIM24TYRTRIM33CYP1A2 | |
| SCHEMBL2933117 | 0.77 | KDM4E (0.55) | ALDH1A1TRIM24TYRTRIM33CYP1A2 | |
| Formaldehyde SCHEMBL28854145 | 0.77 | ALDH1A1 (0.92) | ALDH1A1TRIM24TYRTRIM33CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104961735-A | Pyrazoline derivative and application of pyrazoline derivative as tyrosinase inhibitor | UNIV WUHAN TECH | 2015-10-07 | — | — | CN | disclosed |