SCHEMBL172939

SCHEMBL172939

COc1ccc(OC)c(C=O)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.71
ERN1 O75460 3/20 0.63
CYP1A1 P04798 3/20 0.61
CYP1B1 Q16678 3/20 0.61
NFE2L2 Q16236 3/20 0.61
CYP1A2 P05177 2/20 0.61
JUN P05412 1/20 0.61
NFKB1 P19838 1/20 0.61
TUBB1 Q9H4B7 1/20 0.59
TRIM24 O15164 1/20 0.58
TYR P14679 1/20 0.58
TRIM33 Q9UPN9 1/20 0.58
KDM4E B2RXH2 1/20 0.57
TSHR P16473 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56
CA2 P00918 1/20 0.56
CA7 P43166 1/20 0.56
CA9 Q16790 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29392394 1.00 ALDH1A1 (0.71) ALDH1A1ERN1CYP1A1CYP1B1NFE2L2
3,4-Dimethoxybenzaldehyde SCHEMBL5803811 0.88 ALDH1A1 (0.71) ALDH1A1ERN1CYP1A1CYP1B1NFE2L2
Acetohydroxamic Acid SCHEMBL27553811 0.87 JUN (0.56) ALDH1A1ERN1CYP1A1CYP1B1NFE2L2
SCHEMBL18885196 0.86 TUBB1 (0.55) ALDH1A1ERN1CYP1A1CYP1B1NFE2L2
SCHEMBL50950 0.85 ALDH1A1 (0.58) ALDH1A1ERN1CYP1A1CYP1B1NFE2L2
SCHEMBL4599003 0.85 TUBB1 (0.54) ALDH1A1ERN1CYP1A1CYP1B1NFE2L2
SCHEMBL27930595 0.84 ALDH1A1 (0.57) ALDH1A1ERN1CYP1A1CYP1B1NFE2L2
SCHEMBL1759669 0.84 CYP1A1 (0.58) ALDH1A1ERN1CYP1A1CYP1B1NFE2L2
SCHEMBL24765223 0.83 TUBB1 (0.64) ALDH1A1ERN1CYP1A1CYP1B1NFE2L2
SCHEMBL7591800 0.83 ERN1 (0.59) ALDH1A1ERN1CYP1A1CYP1B1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1872 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12234384-B2 Adhesion-improving composition for textile material and associated reinforcing textile material PORCHER INDUSTRIES (FR) 2025-02-25 US claimed
CN-114181097-B Synthesis method of methoxamine hydrochloride 广东嘉博制药有限公司 2024-05-14 CN claimed
CN-117683820-A Method for preparing aromatic alpha-hydroxy ketone by utilizing acetohydroxy acid synthase 厦门大学 2024-03-12 CN claimed
US-11918671-B2 Multi-tone hair dyeing method in three steps HENKEL AG & CO. KGAA (DE) 2024-03-05 US claimed
CN-113620919-B Mechanical ball milling assisted synthesis method of 2-amino-3-cyano-4H-pyran compound 浙江工业大学 2023-12-12 CN claimed
CN-116818874-A Method for detecting mycotoxin by using multifunctional portable electrochemical technology 江苏大学 2023-09-29 CN claimed
CN-113717037-B Green synthesis method of 2, 5-dimethoxy benzaldehyde 镇江中智化学科技有限公司 2023-09-12 CN claimed
US-11596716-B2 Compounds and matrices for use in bone growth and repair HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2023-03-07 US claimed
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS HENKEL AG & CO. KGAA (DE) 2023-02-02 US claimed
US-20220257483-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL HENKEL AG & CO. KGAA (DE) 2022-08-18 US claimed
EP-0382411-A2 Delivery of cytotoxic agents ELI LILLY AND COMPANY (US) 1990-08-16 EP claimed
EP-0104309-B1 CATALYSTS FOR ALKOXYLATION REACTIONS VISTA CHEMICAL COMPANY (US) 1987-08-05 EP claimed
EP-0105080-B1 A METHOD FOR ALKOXYLATION VISTA CHEMICAL COMPANY (US) 1987-07-01 EP claimed
EP-0105080-A2 A method for alkoxylation VISTA CHEMICAL COMPANY (US) 1984-04-11 EP claimed
EP-0104309-A2 Catalysts for alkoxylation reactions VISTA CHEMICAL COMPANY (US) 1984-04-04 EP claimed
US-4380629-A Styryl-like compounds showing a color-developing and bleaching behavior with improved stability and prolonged lifetime MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) 1983-04-19 US claimed
US-4376868-A Alkoxylation of cresylic acids CONOCO INC. (US) 1983-03-15 US claimed
EP-0049358-A1 Strontium and barium containing alkoxylation systems for unsaturated alcohols Conoco Phillips Company (US) 1982-04-14 EP claimed
EP-0046947-A1 Strontium and barium containing alkoxylation systems Conoco Phillips Company (US) 1982-03-10 EP claimed
US-4147862-A Method of preparing styryl-like compounds MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1979-04-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11596716-B2 Compounds and matrices for use in bone growth and repair BMP2, BMP4, BMP6 ALDH1A1 1413/4885ERN1 4370/4885CYP1A1 4408/4885
US-20220257483-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL KRT18, VIM, CDH1 ALDH1A1 143/4885ERN1 2313/4885CYP1A1 1481/4885
US-11918671-B2 Multi-tone hair dyeing method in three steps TYR, HAO2, HAAO ALDH1A1 111/4885ERN1 4459/4885CYP1A1 428/4885
US-20230031764-A1 MULTI-TONE HAIR DYEING METHOD IN THREE STEPS TYR, HAO2, HAAO ALDH1A1 111/4885ERN1 4459/4885CYP1A1 428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.