Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.52 |
| ▸ | CASR | P41180 | 1/20 | 0.51 |
| ▸ | KLK7 | P49862 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9614867 | 0.82 | NPC1 (0.57) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL701232 | 0.81 | KMT2A (0.54) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL18137202 | 0.81 | KMT2A (0.54) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL28034463 | 0.81 | KLKB1 (0.48) | KMT2AMEN1KLK7POLBHTT | |
| SCHEMBL28034469 | 0.80 | RAB9A (0.48) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL11329740 | 0.79 | KMT2A (0.56) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL3836963 | 0.79 | ROCK2 (0.58) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL5228032 | 0.79 | KMT2A (0.56) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL6723553 | 0.79 | ROCK2 (0.58) | KMT2AMEN1GAAATMGPR55 | |
| SCHEMBL2681667 | 0.77 | KMT2A (0.59) | KMT2AMEN1GAAATMGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104860836-A | Method for oxidizing methylene of 1,3-dicarbonyl compound to form ketone | UNIV HENAN NORMAL | 2015-08-26 | — | — | CN | disclosed |