Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 6/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222527 | 0.89 | KDM4E (0.50) | KDM4EATMALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11858150 | 0.88 | KDM4E (0.49) | KDM4EATMALDH1A1MEN1KMT2A | |
| SCHEMBL11219891 | 0.86 | HTR1D (0.52) | KDM4EATMALDH1A1MEN1KMT2A | |
| SCHEMBL9213988 | 0.86 | GPR84 (0.41) | PDE3BPDE3AMCL1ALBBCL2 | |
| SCHEMBL11287477 | 0.84 | MCL1 (0.43) | PDE3BPDE3AMCL1ALBBCL2 | |
| SCHEMBL11324130 | 0.79 | CYP1A2 (0.44) | PDE3BPDE3AMCL1ALBBCL2 | |
| SCHEMBL11319689 | 0.79 | ADRB2 (0.42) | MCL1ALBBCL2KDM4EATM | |
| SCHEMBL11733248 | 0.78 | CYP1A2 (0.55) | KDM4EALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL11278209 | 0.78 | POLB (0.43) | PDE3BPDE3AMCL1ALBBCL2 | |
| SCHEMBL11225424 | 0.78 | HTR1B (0.43) | KDM4EATMALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105367583-A | THIENO[2, 3-B]PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS | UNIV LEUVEN KATH | 2016-03-02 | — | — | CN | disclosed |
| CN-102459280-B | Thieno [2,3-b ] pyridine derivatives as inhibitors of viral replication | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2015-10-14 | — | — | CN | disclosed |