Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 4/20 | 0.42 |
| ▸ | PARP1 | P09874 | 9/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7600366 | 0.75 | HTR3A (0.59) | HTR3AHTR6PARP1NPY5RPIM1 | |
| SCHEMBL28034227 | 0.74 | HTR3A (0.51) | HTR3AHTR6PARP1NPY5RPIM1 | |
| SCHEMBL28295652 | 0.74 | NUDT1 (0.41) | PIM1 | |
| SCHEMBL20449682 | 0.71 | PARP1 (0.56) | HTR3AHTR6PARP1 | |
| SCHEMBL17697629 | 0.71 | CRBN (0.59) | HTR3AHTR6PARP1 | |
| SCHEMBL5621808 | 0.70 | PARP1 (0.72) | PARP1 | |
| SCHEMBL6869623 | 0.70 | PARP1 (0.49) | HTR3AHTR6PARP1NPY5R | |
| SCHEMBL27802835 | 0.69 | MGAM (0.59) | PARP1 | |
| SCHEMBL7341282 | 0.68 | BCHE (0.54) | HTR3AHTR6PARP1NPY5RDRD2 | |
| SCHEMBL1066810 | 0.68 | HTR3A (0.56) | HTR3AHTR6PARP1NPY5RPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104981468-A | Benzimidazole-2-piperazine heterocyclic compound, pharmaceutical composition thereof, preparation method and use thereof | SHANGHAI HUILUN LIFE SCIENCE & TECHNOLOGY CO LTD | 2015-10-14 | — | — | CN | disclosed |