Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 7/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CTSA | P10619 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28034288 | 0.85 | REN (0.47) | RENSMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL1423244 | 0.85 | REN (0.40) | RENKCNN4NPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3456050 | 0.77 | KCNN4 (0.42) | KCNN4NPSR1SMN1; SMN2ALDH1A1CTSA | |
| SCHEMBL2219776 | 0.77 | REN (0.37) | RENKCNN4SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1422745 | 0.73 | HTT (0.42) | RENALDH1A1LMNAKDM4EMEN1 | |
| SCHEMBL2221206 | 0.73 | ALDH1A1 (0.39) | RENSMN1; SMN2ALDH1A1LMNAKDM4E | |
| SCHEMBL12441525 | 0.73 | REN (0.58) | REN | |
| SCHEMBL2220615 | 0.73 | REN (0.51) | REN | |
| SCHEMBL12441480 | 0.73 | REN (0.60) | REN | |
| SCHEMBL12441484 | 0.73 | REN (0.60) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103373985-B | Heterocyclic compounds and their use | TAKEDA PHARMACEUTICAL CO.,LTD. (JP) | 2015-10-28 | — | — | CN | disclosed |