Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 4/20 | 0.39 |
| ▸ | CPB1 | P15086 | 2/20 | 0.39 |
| ▸ | KDM5A | P29375 | 2/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30268827 | 0.83 | PLA2G4A (0.52) | PLA2G4ACPB2CPB1KDM5AKDM5B | |
| SCHEMBL27781577 | 0.81 | PLA2G4A (0.54) | PLA2G4ACPB2CPB1KDM5AKDM5B | |
| SCHEMBL27781551 | 0.81 | PLA2G4A (0.54) | PLA2G4ACPB2CPB1KDM5AKDM5B | |
| SCHEMBL2283649 | 0.81 | PLA2G4A (0.50) | PLA2G4ACPB2CPB1KDM5AKDM5B | |
| SCHEMBL14151866 | 0.79 | PLA2G4A (0.42) | PLA2G4AKDM5AKDM5BHCAR2KDM4E | |
| SCHEMBL710279 | 0.77 | KDM5A (0.54) | PLA2G4ACPB2CPB1KDM5AKDM5B | |
| SCHEMBL29852373 | 0.75 | TNF (0.47) | PLA2G4ATBXAS1 | |
| SCHEMBL7265607 | 0.75 | PLA2G4A (0.39) | PLA2G4ACPB2KDM5AKDM5BKDM2B | |
| SCHEMBL151394 | 0.73 | SMYD3 (0.50) | PLA2G4ACPB2CPB1KDM5AKDM5B | |
| SCHEMBL5726708 | 0.73 | CPB2 (0.45) | PLA2G4ACPB2CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103373985-B | Heterocyclic compounds and their use | TAKEDA PHARMACEUTICAL CO.,LTD. (JP) | 2015-10-28 | — | — | CN | disclosed |