Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28034294 | 0.89 | PPARG (0.42) | PPARGRENHTTTP53SMN1; SMN2 | |
| SCHEMBL2221448 | 0.87 | CA1 (0.44) | PPARGRENHTTTP53SMN1; SMN2 | |
| SCHEMBL2219018 | 0.87 | HTT (0.52) | PPARGRENHTTTP53SMN1; SMN2 | |
| SCHEMBL2221627 | 0.86 | PTGS2 (0.46) | PPARGRENHTTTP53SMN1; SMN2 | |
| SCHEMBL2219586 | 0.86 | SMN1; SMN2 (0.47) | PPARGRENHTTTP53SMN1; SMN2 | |
| SCHEMBL2217094 | 0.86 | PTGS2 (0.46) | PPARGRENHTTL3MBTL1POLB | |
| SCHEMBL2220649 | 0.81 | ALDH1A1 (0.42) | PPARGRENHTTTP53SMN1; SMN2 | |
| SCHEMBL2223484 | 0.81 | HSD11B1 (0.47) | PPARGRENHTTTP53SMN1; SMN2 | |
| SCHEMBL2218506 | 0.81 | GAA (0.51) | PPARGRENHTTSMN1; SMN2NPC1 | |
| SCHEMBL2218858 | 0.81 | ALDH1A1 (0.43) | PPARGRENHTTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103373985-B | Heterocyclic compounds and their use | TAKEDA PHARMACEUTICAL CO.,LTD. (JP) | 2015-10-28 | — | — | CN | disclosed |