Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | ATM | Q13315 | 2/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16610194 | 0.82 | DEGS1 (0.61) | KMT2AMEN1RAB9AGAAHPGD | |
| SCHEMBL3166771 | 0.82 | SMN1; SMN2 (0.69) | KMT2AMEN1ATMHDAC3HDAC4 | |
| SCHEMBL9312728 | 0.81 | HDAC3 (0.66) | KMT2AMEN1ATMHDAC3HDAC4 | |
| SCHEMBL9508626 | 0.80 | KMT2A (0.63) | KMT2AMEN1RAB9AGAAHPGD | |
| SCHEMBL4112929 | 0.80 | RAB9A (0.69) | KMT2AMEN1ATMRAB9AGAA | |
| SCHEMBL4866611 | 0.77 | ALDH1A1 (0.64) | KMT2AMEN1ATMRAB9AGAA | |
| SCHEMBL20851771 | 0.76 | POLB (0.74) | KMT2AMEN1ATMHDAC3HDAC4 | |
| SCHEMBL13381412 | 0.76 | HDAC3 (0.60) | KMT2AMEN1ATMHDAC3HDAC4 | |
| SCHEMBL7055067 | 0.76 | POLB (0.70) | KMT2AMEN1ATMHDAC3HDAC4 | |
| SCHEMBL826066 | 0.76 | HDAC3 (0.64) | KMT2AMEN1ATMHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085433-B | Substituted amide phenol compound and preparation method thereof, pharmaceutical composition and purposes | 中国科学院上海药物研究所 | 2019-06-25 | — | — | CN | disclosed |
| CN-105085433-A | Substituted-amide phenolic compound, preparation method, pharmaceutical composition and application thereof | SHANGHAI INST MATERIA MEDICA | 2015-11-25 | — | — | CN | disclosed |