(Chloromethyl)Benzene

(Chloromethyl)Benzene

SCHEMBL28034643

C=CC(=O)OCCN(C)C.ClCc1ccccc1.N

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 2/20 0.48
THRB P10828 1/20 0.48
ALDH1A1 P00352 4/20 0.43
HRH1 P35367 2/20 0.41
TDP1 Q9NUW8 2/20 0.40
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40
MAPT P10636 1/20 0.40
PKM P14618 1/20 0.40
RECQL P46063 1/20 0.40
CACNA1B Q00975 1/20 0.40
APBA1 Q02410 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
LMNA P02545 2/20 0.39
CHRM2 P08172 1/20 0.39
CHRM3 P20309 1/20 0.39
BCHE P06276 1/20 0.39
LTA4H P09960 1/20 0.38
HCAR2 Q8TDS4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Chloromethyl)Benzene SCHEMBL169630 0.99 CHRM1 (0.49) CHRM1THRBALDH1A1HRH1TDP1
(Chloromethyl)Benzene SCHEMBL28396267 0.97 CHRM1 (0.48) CHRM1THRBALDH1A1HRH1TDP1
(Chloromethyl)Benzene SCHEMBL30158925 0.90 CHRM1 (0.43) CHRM1THRBALDH1A1HRH1TDP1
(Chloromethyl)Benzene SCHEMBL28529363 0.85 LMNA (0.50) CHRM1THRBALDH1A1POLBSMN1; SMN2
Hydrochloric Acid SCHEMBL28002276 0.85 CHRM1 (0.49) CHRM1THRBALDH1A1HRH1TDP1
Benzylamine SCHEMBL28520485 0.85 CHRM1 (0.49) CHRM1THRBALDH1A1HRH1TDP1
(Chloromethyl)Benzene SCHEMBL8070807 0.85 THRB (0.44) CHRM1THRBALDH1A1TDP1MAPT
SCHEMBL28002275 0.84 CHRM1 (0.46) CHRM1THRBALDH1A1HRH1TDP1
Benzylamine SCHEMBL27761870 0.84 CHRM1 (0.48) CHRM1THRBALDH1A1HRH1TDP1
(Chloromethyl)Benzene SCHEMBL28976987 0.83 THRB (0.43) CHRM1THRBALDH1A1TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105237648-A Highly-branched starch modified by glyoxal crosslinked polymer, preparation method and application thereof ZHAO YINGHUI 2016-01-13 CN disclosed
CN-105111378-A Cationic polymer grafting modified nanocrystalline cellulose and preparation method and application thereof ZHAO YINGHUI 2015-12-02 CN disclosed
CN-105086322-A Glyoxal cross-linked polymer modified nano crystalline cellulose as well as preparation method and application thereof ZHAO YINGHUI 2015-11-25 CN disclosed