Dl-Tryptophan

Dl-Tryptophan

SCHEMBL28034780

NC(Cc1c[nH]c2ccccc12)C(=O)O.O=C(O)C(=O)Cc1ccccc1

nearest known ligand 0.78

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.78
KDM4E B2RXH2 4/20 0.78
MAPT P10636 4/20 0.78
MEN1 O00255 3/20 0.78
LMNA P02545 2/20 0.78
TSHR P16473 2/20 0.78
BLM P54132 2/20 0.78
PMP22 Q01453 2/20 0.78
MPO P05164 1/20 0.78
HIF1A Q16665 1/20 0.78
SLC6A2 P23975 2/20 0.64
FNTA P49354 1/20 0.64
FNTB P49356 1/20 0.64
SMN1; SMN2 Q16637 2/20 0.63
ALDH1A1 P00352 2/20 0.63
HPGD P15428 1/20 0.63
HSP90AA1 P07900 1/20 0.57
HSP90AB1 P08238 1/20 0.57
LTA4H P09960 1/20 0.57
PLA2G2A P14555 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tryptophan SCHEMBL29884112 1.00 KMT2A (0.78) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL2174790 0.93 KDM4E (0.82) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL2174795 0.93 KDM4E (0.82) KMT2AKDM4EMAPTMEN1LMNA
D-Tryptophan SCHEMBL2176030 0.93 KDM4E (0.82) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL9067245 0.89 KMT2A (0.80) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL27641165 0.89 KMT2A (0.89) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL120930 0.89 KMT2A (0.89) KMT2AKDM4EMAPTMEN1LMNA
Dl-Tryptophan SCHEMBL120929 0.89 KMT2A (0.89) KMT2AKDM4EMAPTMEN1LMNA
D-Tryptophan SCHEMBL11869971 0.89 KMT2A (0.89) KMT2AKDM4EMAPTMEN1LMNA
Tryptophan SCHEMBL31214183 0.88 KMT2A (0.94) KMT2AKDM4EMAPTMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101437954-B The nucleic acid of zymohexase and coding zymohexase and their preparation and application CARGILL, INC. (US) 2015-09-09 CN disclosed