Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DTYMK | P23919 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | TLR4 | O00206 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | PPOX | P50336 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17493027 | 0.86 | TDP1 (0.52) | SIGMAR1TLR4TLR2TDP1PARP10 | |
| SCHEMBL13836687 | 0.83 | SIGMAR1 (0.52) | SIGMAR1TLR4TLR2PARP10PARP15 | |
| SCHEMBL8872227 | 0.80 | MAPT (0.61) | DTYMKMEN1KMT2ATTRPPOX | |
| SCHEMBL27248687 | 0.79 | DTYMK (0.51) | DTYMKMEN1KMT2ATTRPPOX | |
| SCHEMBL30301856 | 0.79 | DTYMK (0.51) | DTYMKMEN1KMT2ATTRPPOX | |
| SCHEMBL2558176 | 0.79 | PARP10 (0.49) | SIGMAR1TLR4TLR2TDP1PARP10 | |
| SCHEMBL28034902 | 0.79 | SIGMAR1 (0.49) | SIGMAR1TLR4TLR2PARP10PARP15 | |
| SCHEMBL27038419 | 0.79 | SIGMAR1 (0.49) | SIGMAR1TLR4TLR2MEN1KMT2A | |
| SCHEMBL29739999 | 0.79 | PARP10 (0.49) | SIGMAR1TLR4TLR2TDP1PARP10 | |
| SCHEMBL31536503 | 0.79 | PARP10 (0.50) | PARP10PARP15PARP2NR1H4KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107337621-A | Dicarboxylic acid compound | 第三共株式会社 | 2017-11-10 | — | — | CN | disclosed |
| CN-107311895-A | Dicarboxylic acid compound | 第三共株式会社 | 2017-11-03 | — | — | CN | disclosed |
| EP-2990400-B1 | DICARBOXYLIC ACID COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2017-06-21 | — | — | EP | disclosed |
| US-9670173-B2 | Dicarboxylic acid compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-06-06 | — | — | US | disclosed |
| US-9617232-B2 | Dicarboxylic acid compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-04-11 | — | — | US | disclosed |
| US-20170015641-A1 | DICARBOXYLIC ACID COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-01-19 | — | — | US | disclosed |
| EP-2990400-A1 | DICARBOXYLIC ACID COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-03-02 | — | — | EP | disclosed |
| US-20160046568-A1 | DICARBOXYLIC ACID COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2016-02-18 | — | — | US | disclosed |
| CN-105121405-A | Dicarboxylic acid compound | DAIICHI SANKYO CO LTD | 2015-12-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170015641-A1 | DICARBOXYLIC ACID COMPOUND | CA2, HCAR2, SLC5A2 | DTYMK 2300/4885SIGMAR1 2245/4885TLR4 3016/4885 |
| US-20160046568-A1 | DICARBOXYLIC ACID COMPOUND | CA2, HCAR2, SLC5A2 | DTYMK 2300/4885SIGMAR1 2245/4885TLR4 3016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.