Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20633452 | 0.92 | FDPS (0.36) | FDPSTP53SMN1; SMN2KDM4EGMNN | |
| SCHEMBL17733703 | 0.82 | SIGMAR1 (0.41) | TP53SMN1; SMN2KDM4EGMNNLMNA | |
| SCHEMBL17827126 | 0.82 | DPP4 (0.33) | FDPSTP53 | |
| SCHEMBL14103774 | 0.82 | SMN1; SMN2 (0.33) | FDPSSMN1; SMN2EPHX1 | |
| SCHEMBL22628621 | 0.79 | CPN1 (0.33) | KDM4ELMNATSHR | |
| SCHEMBL19631132 | 0.79 | KDM4E (0.42) | TP53SMN1; SMN2KDM4ELMNAMAPT | |
| SCHEMBL23716166 | 0.75 | HRH3 (0.38) | KDM4EMAPT | |
| SCHEMBL15451117 | 0.73 | — | — | |
| SCHEMBL14655522 | 0.72 | EPHX1 (0.52) | FDPSEPHX1HTTTSHR | |
| SCHEMBL19513190 | 0.70 | HSD11B1 (0.44) | TP53SMN1; SMN2KDM4EGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103025725-B | Heterocyclic compounds | ASTELLAS PHARMA INC. (JP) | 2015-09-16 | — | — | CN | disclosed |