Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698031 | 0.85 | NR4A2 (0.53) | NR4A2ALDH1A1LMNAKMT2AMITF | |
| SCHEMBL3416860 | 0.85 | NR4A2 (0.53) | NR4A2ALDH1A1LMNAKMT2AMITF | |
| SCHEMBL2350154 | 0.82 | NR4A2 (0.50) | NR4A2ALDH1A1LMNAKMT2AMITF | |
| SCHEMBL28034933 | 0.81 | NR4A2 (0.49) | NR4A2ALDH1A1LMNAKMT2AMITF | |
| SCHEMBL28095904 | 0.80 | NR4A2 (0.48) | NR4A2ALDH1A1LMNAKMT2AMITF | |
| SCHEMBL9283137 | 0.78 | NR4A2 (0.45) | NR4A2ALDH1A1LMNAKMT2AMITF | |
| SCHEMBL30773378 | 0.75 | NR4A2 (0.47) | NR4A2ALDH1A1LMNAKMT2AMITF | |
| SCHEMBL12614276 | 0.74 | GPR84 (0.52) | NR4A2ALDH1A1KMT2ANPSR1POLB | |
| SCHEMBL10863583 | 0.74 | ALDH1A1 (0.51) | NR4A2ALDH1A1LMNAKMT2AMITF | |
| SCHEMBL1122106 | 0.74 | PRKCA (0.47) | NR4A2KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610487-B1 | NEW AMINOACID DERIVATES, PROCESS FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | BOEHRINGER INGELHEIM PHARMA (DE) | 1999-11-10 | — | — | EP | disclosed |