Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | HTR3A | P46098 | 2/20 | 0.52 |
| ▸ | TNF | P01375 | 1/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.51 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2641012 | 0.87 | CFTR (0.56) | CFTRPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5166005 | 0.86 | MAPK1 (0.58) | KMT2AALDH1A1CYP1A2CYP2D6LMNA | |
| SCHEMBL7341277 | 0.82 | HTR3A (0.75) | MEN1KMT2ACYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL12825173 | 0.78 | CFTR (0.56) | CFTRMEN1KMT2AALDH1A1 | |
| SCHEMBL29249923 | 0.76 | CFTR (0.56) | CFTRMEN1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL28898444 | 0.76 | CFTR (0.67) | CFTRMEN1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL15568337 | 0.75 | CYP1A2 (0.97) | MEN1KMT2ACYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL29497996 | 0.74 | CFTR (1.00) | CFTRMEN1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL19032859 | 0.74 | CFTR (1.00) | CFTRMEN1KMT2ACYP2C19ALDH1A1 | |
| SCHEMBL31315686 | 0.74 | CFTR (0.51) | CFTRMEN1KMT2ACYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105001169-A | Synthetic method for 3-aminoquinoxaline-2(1H)-ketone compound | UNIV HUAQIAO | 2015-10-28 | — | — | CN | disclosed |