SCHEMBL31315686

SCHEMBL31315686

O=c1c(C(O)C2CCCCC2)nc2ccccc2n1Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFTR P13569 3/20 0.51
PDE6D O43924 3/20 0.51
CNR1 P21554 1/20 0.48
CNR2 P34972 1/20 0.48
PDE4A P27815 1/20 0.48
PDE4B Q07343 1/20 0.48
PDE4C Q08493 1/20 0.48
PDE4D Q08499 1/20 0.48
TDP1 Q9NUW8 1/20 0.47
MAPK1 P28482 1/20 0.47
MC4R P32245 1/20 0.47
ALDH1A1 P00352 2/20 0.46
ALDH2 P05091 1/20 0.46
ALDH3A1 P30838 1/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP2C9 P11712 2/20 0.45
CYP2C19 P33261 2/20 0.45
FGFR1 P11362 1/20 0.45
FGFR3 P22607 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31315695 0.88 ALDH1A1 (0.51) TDP1MAPK1ALDH1A1SMN1; SMN2NPSR1
SCHEMBL31315692 0.83 SMN1; SMN2 (0.46) CFTRMAPK1ALDH1A1MEN1KMT2A
SCHEMBL31315701 0.80 KMT2A (0.47) TDP1MAPK1ALDH1A1MEN1KMT2A
SCHEMBL31315690 0.78 TP53 (0.46) ALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL29249923 0.77 CFTR (0.56) CFTRPDE6DPDE4APDE4BPDE4C
SCHEMBL28034992 0.77 CFTR (0.53) CFTRCNR1CNR2PDE4APDE4B
SCHEMBL29037523 0.76 CFTR (0.62) CFTRPDE6DPDE4APDE4BPDE4C
SCHEMBL28034968 0.74 CFTR (0.59) CFTRPDE6DPDE4APDE4BPDE4C
SCHEMBL7897746 0.72 HTR3A (0.53) PDE6DALDH1A1ALDH2ALDH3A1MEN1
SCHEMBL6579407 0.70 CFTR (0.63) CFTRPDE6DPDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115233244-B Method for electrochemically synthesizing 3-hydroxyalkyl quinoxaline-2 (1H) -ketone compound 桂林医学院 2024-12-27 CN disclosed