Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 6/20 | 0.37 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.37 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 3/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.33 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023323 | 0.80 | MCL1 (0.41) | CHUKARIMPDH2IMPDH1PGR | |
| SCHEMBL28035241 | 0.75 | CHUK (0.42) | CHUKARCYP11B1CYP11B2ADORA2A | |
| SCHEMBL28035135 | 0.74 | DYRK1A (0.35) | ARLRRK2 | |
| SCHEMBL9023027 | 0.71 | MCL1 (0.44) | ARLRRK2 | |
| SCHEMBL28034516 | 0.71 | AR (0.33) | ARLRRK2 | |
| SCHEMBL1605889 | 0.70 | PDK2 (0.46) | CHUKCUL4ACYP11B1CYP11B2PDK2 | |
| SCHEMBL28034518 | 0.69 | KDM4E (0.36) | ARCYP11B1CYP11B2LRRK2 | |
| SCHEMBL12670741 | 0.67 | CHUK (0.47) | CHUKCUL4AIMPDH2IMPDH1CYP11B1 | |
| SCHEMBL28828309 | 0.67 | CHUK (0.43) | CHUKCUL4AIMPDH2IMPDH1CYP11B1 | |
| SCHEMBL2650416 | 0.67 | ESR2 (0.48) | CHUKCUL4ACYP11B1CYP11B2PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104982435-A | Biocide composition comprising pyrithione and pyrrole derivatives | ARCH CHEM INC | 2015-10-21 | — | — | CN | disclosed |