SCHEMBL28035135

SCHEMBL28035135

N#Cc1c[nH]c(C(F)(F)F)c1-c1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 1/20 0.35
AR P10275 5/20 0.33
LRRK2 Q5S007 2/20 0.33
AHR P35869 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28034516 0.80 AR (0.33) DYRK1AARLRRK2
SCHEMBL9023027 0.75 MCL1 (0.44) DYRK1AARLRRK2
SCHEMBL4748506 0.74 DYRK1A (0.37) DYRK1AARLRRK2
SCHEMBL28035243 0.74 CHUK (0.44) ARLRRK2
SCHEMBL28034518 0.73 KDM4E (0.36) DYRK1AARLRRK2
SCHEMBL9023323 0.71 MCL1 (0.41) DYRK1AARLRRK2
SCHEMBL28035241 0.70 CHUK (0.42) AR
SCHEMBL1180449 0.67 KDM4E (0.34)
SCHEMBL28025393 0.64 NOTUM (0.47) AR
SCHEMBL30761205 0.63 DPYD (0.42) DYRK1ALRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104982435-A Biocide composition comprising pyrithione and pyrrole derivatives ARCH CHEM INC 2015-10-21 CN disclosed