Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.35 |
| ▸ | AR | P10275 | 6/20 | 0.34 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9023027 | 0.86 | MCL1 (0.44) | KDM4EMCL1LRRK2ARPSD | |
| SCHEMBL28034516 | 0.79 | AR (0.33) | MCL1LRRK2ARPSDALDH1A1 | |
| SCHEMBL9023323 | 0.79 | MCL1 (0.41) | KDM4EMCL1LRRK2ARALDH1A1 | |
| SCHEMBL28035241 | 0.77 | CHUK (0.42) | KDM4EARALDH1A1GAAHPGD | |
| SCHEMBL4748506 | 0.75 | DYRK1A (0.37) | MCL1LRRK2ARDYRK1A | |
| SCHEMBL28035135 | 0.73 | DYRK1A (0.35) | LRRK2ARDYRK1A | |
| SCHEMBL3896879 | 0.69 | KDM4E (0.35) | KDM4EARPSDALDH1A1LMNA | |
| SCHEMBL28035243 | 0.69 | CHUK (0.44) | LRRK2ARCYP11B1CYP11B2 | |
| SCHEMBL1180128 | 0.66 | ALDH1A1 (0.39) | KDM4EPSDALDH1A1LMNAGLA | |
| SCHEMBL10441636 | 0.65 | AR (0.42) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104982435-A | Biocide composition comprising pyrithione and pyrrole derivatives | ARCH CHEM INC | 2015-10-21 | — | — | CN | disclosed |