Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.64 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26154069 | 0.81 | EPHX2 (0.90) | NPC1EPHX2TDP1KMT2AMEN1 | |
| SCHEMBL13498400 | 0.81 | EPHX2 (0.70) | NPC1EPHX2TDP1KMT2AMEN1 | |
| SCHEMBL3101265 | 0.78 | NPC1 (0.50) | NPC1EPHX2TDP1KMT2AMEN1 | |
| SCHEMBL30814172 | 0.78 | NPC1 (0.50) | NPC1EPHX2TDP1KMT2AMEN1 | |
| SCHEMBL5308393 | 0.78 | RAB9A (0.73) | NPC1EPHX2TDP1KMT2AMEN1 | |
| SCHEMBL12931994 | 0.78 | EPHX2 (1.00) | NPC1EPHX2TDP1KMT2AMEN1 | |
| SCHEMBL4866294 | 0.78 | EPHX2 (0.97) | NPC1EPHX2TDP1KMT2AMEN1 | |
| SCHEMBL13930864 | 0.78 | GPR119 (0.56) | EPHX2KMT2A | |
| SCHEMBL29076764 | 0.77 | NPSR1 (0.63) | NPC1TDP1KMT2AMEN1RAB9A | |
| SCHEMBL20852858 | 0.77 | RAB9A (0.71) | NPC1EPHX2TDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104995191-A | Tricyclic quinoline and quinoxaline derivatives | ABBVIE DEUTSCHLAND | 2015-10-21 | — | — | CN | disclosed |